Docusate sodium
Docusate sodium is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Events Timeline
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YTD
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2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
Therapeutic Areas
Therapeutic Area | MeSH |
|---|---|
| signs and symptoms pathological conditions | D013568 |
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| basic care stool softener | C200263 | 2024-06-14 |
| betr remedies stool softener | C200263 | 2024-10-30 |
| chupanzon colon detox | C200263 | 2023-11-16 |
| citranatal 90 dha | unapproved drug other | 2024-01-08 |
| citranatal assure | unapproved drug other | 2024-01-08 |
| citranatal bloom dha | unapproved drug other | 2020-04-06 |
| citranatal dha | unapproved drug other | 2020-07-28 |
| citranatal essence | unapproved drug other | 2020-07-07 |
| citranatal harmony | unapproved drug other | 2012-01-18 |
| citranatal harmony 2.1 | unapproved drug other | 2019-05-14 |
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Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
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Patent Expiration
No data
HCPCS
No data
Clinical
Clinical Trials
89 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Constipation | D003248 | — | K59.0 | — | 4 | 3 | 6 | 2 | 13 |
| Infections | D007239 | EFO_0000544 | — | — | 1 | 1 | 5 | — | 7 |
| Diarrhea | D003967 | — | R19.7 | — | — | 1 | 1 | 1 | 3 |
| Analgesia | D000698 | — | — | — | — | — | 1 | 1 | 2 |
| Psychotic disorders | D011618 | — | F20.81 | — | 1 | 1 | 1 | — | 2 |
| Ileus | D045823 | — | K56.7 | 1 | — | — | 1 | — | 2 |
| Covid-19 | D000086382 | — | U07.1 | — | — | — | 1 | 1 | 2 |
| Paralysis | D010243 | — | — | — | — | — | 1 | — | 1 |
| Helicobacter infections | D016481 | EFO_1000961 | — | — | — | — | 1 | — | 1 |
| Morbid obesity | D009767 | EFO_0001074 | — | — | — | — | 1 | — | 1 |
Show 3 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Post-dural puncture headache | D051299 | — | — | — | — | 1 | — | 1 | 2 |
| Communicable diseases | D003141 | — | — | — | 1 | 1 | — | — | 2 |
| Gastritis | D005756 | EFO_0000217 | K29.7 | — | — | 1 | — | 1 | 2 |
| 22q11 deletion syndrome | D058165 | Orphanet_567 | D82.1 | — | 1 | 1 | — | — | 1 |
| Female genital diseases | D005831 | EFO_0009549 | N85 | — | 1 | 1 | — | — | 1 |
| Chronic obstructive pulmonary disease | D029424 | EFO_0000341 | J44.9 | — | — | 1 | — | — | 1 |
| Obstructive lung diseases | D008173 | — | — | — | — | 1 | — | — | 1 |
| Dyspnea | D004417 | — | R06.0 | — | — | 1 | — | — | 1 |
| Cytomegalovirus infections | D003586 | EFO_0001062 | B25 | — | — | 1 | — | — | 1 |
| Anterior cruciate ligament injuries | D000070598 | — | — | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Non-small-cell lung carcinoma | D002289 | — | — | — | 2 | — | — | 1 | 3 |
| Lung neoplasms | D008175 | — | C34.90 | — | 2 | — | — | — | 2 |
| Liver neoplasms | D008113 | EFO_1001513 | C22.0 | — | 1 | — | — | 1 | 2 |
| Glioblastoma | D005909 | EFO_0000515 | — | 2 | 1 | — | — | — | 2 |
| Lymphoma | D008223 | — | C85.9 | — | 2 | — | — | — | 2 |
| Halitosis | D006209 | — | R19.6 | 2 | 1 | — | — | — | 2 |
| Adenocarcinoma | D000230 | — | — | — | 1 | — | — | — | 1 |
| Squamous cell carcinoma | D002294 | — | — | — | 1 | — | — | — | 1 |
| Squamous cell neoplasms | D018307 | — | — | — | 1 | — | — | — | 1 |
| Brain neoplasms | D001932 | EFO_0003833 | C71 | — | 1 | — | — | — | 1 |
Show 24 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 2 | — | — | — | 1 | 3 |
| Hyperacusis | D012001 | — | H93.23 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Agnosia | D000377 | EFO_0007136 | F88 | — | — | — | — | 2 | 2 |
| Intestinal diseases | D007410 | — | K63.9 | — | — | — | — | 2 | 2 |
| Ischemic stroke | D000083242 | — | — | — | — | — | — | 1 | 1 |
| Stroke | D020521 | EFO_0000712 | I63.9 | — | — | — | — | 1 | 1 |
| Atherosclerosis | D050197 | EFO_0003914 | I25.1 | — | — | — | — | 1 | 1 |
| Intracranial arteriosclerosis | D002537 | EFO_1000860 | I67.2 | — | — | — | — | 1 | 1 |
| Microbiota | D064307 | — | — | — | — | — | — | 1 | 1 |
| Liver diseases | D008107 | EFO_0001421 | K70-K77 | — | — | — | — | 1 | 1 |
| Liver cirrhosis | D008103 | EFO_0001422 | K74.0 | — | — | — | — | 1 | 1 |
| End stage liver disease | D058625 | EFO_1001311 | K72.1 | — | — | — | — | 1 | 1 |
Show 51 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Docusate sodium |
| INN | docusate sodium |
| Description | 1,4-bis(2-ethylhexyl) sulfosuccinate is a diester and an organosulfonic acid. |
| Classification | Small molecule |
| Drug class | Stool softener |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CCCCC(CC)COC(=O)CC(C(=O)OCC(CC)CCCC)S(=O)(=O)[O-].[Na+] |
Identifiers
| PDB | — |
| CAS-ID | 577-11-7 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1905872 |
| ChEBI ID | — |
| PubChem CID | 11339 |
| DrugBank | DB11089 |
| UNII ID | F05Q2T2JA0 (ChemIDplus, GSRS) |
Target
No data
Variants
No data
Financial
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Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 4,790 documents
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Safety
Black-box Warning
Black-box warning for: Citranatal 90 dha, Citranatal assure, Citranatal dha, Citranatal essence, Citranatal harmony, Citranatal harmony 2.1, Citranatal harmony 3.0, Citranatal rx, Ferralet 90
Adverse Events
Top Adverse Reactions
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1,826 adverse events reported
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